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New Gout Drugs
#1
Bug 
[size=4][b]Food Good for Gout - New Gout Drugs - Pegloticase Continues Its Hopeful Path[/b][/size][hr]May 2008 the U.S. based company developing Pegloticase made another upbeat statement assessment of what they have learnt in its Phase 3 and open label extension trials. Note that Pegloticase still awaits approval from medical authorities so I am writing here about a new gout drug that is still under development.

May was a good month for gout sufferers. Febuxostat, (EU trade/brand name Adenuric), the first new major drug medication for gout in over 40 years, was approved for marketing in member countries of the European Union.

[size=large][b]Has Been Having a Decent Degree of Success[/b][/size][hr]<strong>Elimination of gout attacks </strong>In its most recent statement the developing company's most significant remark was that the extension trial group receiving Pegloticase every two weeks, there were only four gout attacks among those who had been administered Pegloticase (8 mg) every fortnight for two months, in subsequent months. And none in this group had a gout attack after five months of Pegloticase treatment, in following months. All were patients who had been through a phase 3 trial. It would be hopeless trying to get people who are not interested in knowing more about Treat Gout to read articles pertaining to it. Only people interested in Treat Gout will enjoy this article.

<strong>TRIAL SUCCESS WITH DIFFICULT TO TREAT GOUT PATIENTS </strong> Pegloticase is significant because its trials have focused on gout patients who have not had success with other gout drugs, or who have medical conditions which prohibit the use of them. Thus it has been tackling harder-to-treat gout cases, not the easier ones. Hard to treat cases are a significant percentage of the gout sufferer universe.

[size=large][b]Other Patient Groups There Were Reductions in Attacks and Improvement in Tophi Reduction[/b][/size][hr]Tophi are those knobbly shaped, awkward looking, lumps of MSU crystals that often develop in longer term gout sufferers. A lot of imagination is required in writing. People may think that writing on Uric Acid Level is very easy; on the contrary, knowledge and imagination has to be merged to create an interesting composition.

[list][*]<strong>SIDE EFFECTS </strong> Of course Pegloticase has caused side effects, in the extension trial in about 1 in 5 patients.[*]The developing company has said that most were mild, moderate, or controllable.[*]But in some cases more severe side effects have been described as including chest and back pains, muscle cramps, sweating and flushes.[*]This article has been written with the intention of showing some illumination to the meaning of Gout Attacks.[*]This is so that those who don't know much about Gout Attacks can learn more about it.[/list]

Quote:<strong>HOW PEGLOTICASE WORKS </strong> What makes Pegloticase a very interesting, and more importantly, a hopeful new gout drug, is the way it works. All drugs used in gout try to cure or alleviate the disease by reducing the body's uric acid (UA) levels. They do this by either inhibiting its production or making it easier to remove. The length of an article is rather immaterial about its response from people. People are more interested in the matter about Uric Acid, and not length.

This suggests that progression of the disease may be contained in difficult-to-treat cases, and therefore may not cause other medical conditions such as kidney stones heart disease and hypertension. Reading is a habit that has to be cultivated from a small age. Only if one has the habit of reading can one acquire more knowledge on things like Gout Remedies. Big Grin.

Pegloticase's answer to the excess uric acid level problem is to remove it by ingeniously converting uric acid into something else, a substance called Allantoin. Allantoin is more soluble and better excreted than uric acid. The principle comes from the way most animals do it. They do it by converting UA to Allantoin, but this is something humans cannot do naturally. Hence the formulation of Pegloticase. The more interesting an article, the more takers there are for the article. So we have made it a point to make this article on Gout Sufferer as interesting as possible!

[size=large][b]Pegloticase is Getting Closer to an Application for Approval by the U.S[/b][/size][hr]FDA. Its developers hope to apply for a Biologics Licence Application in September 2008, and begin marketing it in 2009. As we got to writing on Uric Acid Level, we found that the time we were given to write was inadequate to write all that there is to write about Uric Acid Level! So vast are its resources. :o.

[list][*]31% of patients who had not reduced tophi at the end of these phase 3 trials did show tophi reduction in the extension trial.[*]It would seem that the longer a gout sufferer is able to take Pegloticase the more successful it may be, in tophi cases at least.[*]People are inclined to think that some matter found here that is pertaining to Uric Acid is false.[*]However, rest is assured, all that is written here is true![/list]

Other encouraging statements were that all extension trial patients who had responded earlier to treatment and who were on the every two week course maintained normal uric acid levels, (some were new joiners). 70% of those on an every four week course who had responded earlier to treatment, maintained normal uric acid levels.

[size=large][b]You are Searching for a Guaranteed Gout Remedy Report, You Came to the Right Place![/b][/size][hr]Did you know that gout is the most painful form of arthritis but is also the most treatable? If you are suffering from gout, you have the option to allow gout to control you and your life or you can begin to naturally treat gout and take your life back! And the best thing about gout is you can save money and naturally cure gout at home!

[b]4. Neutralizing Acid-[/b] Do you remember your last science class? But seriously, you can naturally neutralize the uric acid between your joints with a baking soda water mix. Baking soda is a base which is just the opposite of an acid. Therefore, by drinking a baking soda concoction, you can naturally treat a flare-up. Ignorance is bliss they say. However, do you find this practical when you read so much about Gout Prevention?

[list][*][b] Lose Weight-[/b] This natural remedy will actually shed the pounds off you too![*]By eating water soluble fiber foods (vegetables and fruits), you can lose weight and cure gout.[*]Water soluble fiber flushes toxins, impurities, excess fat/cholesterol and uric acid.[*]Accept the way things are in life.[*]Only then will you be able to accept these points on Gout Prevention.[*]Gout Prevention can be considered to be part and parcel of life.[/list]

[b]Naturally Cure Gout in 2 Hours of Less[/b] What vitamins should you be taking? What supplements? What breathing techniques increase circulation and keep uric acid levels low? What exercises should you be trying? Make the best use of life by learning and reading as much as possible. read about things unknown, and more about things known, like about Cure Gout Naturally.

[size=large][b]Discover the Only 100% Guaranteed, Step by Step Natural Gout Remedy Report[/b][/size][hr]Our report is researched-based and doctor approved and has helped tens of thousands of gout sufferers. Take a moment and see how you can try our gout remedy report risk-free today at our safe and secured website. life is short. Use it to its maximum by utilizing whatever knowledge it offers for knowledge is important for all walks of life. Even the crooks have to be intelligent!

[list][*][b]Naturally Cure Gout with 5 Free Tips[/b] Here are 5 free secrets to cure gout from our Gout Remedy Report![*]Whenever one reads any reading matter, it is vital that the person enjoys reading it.[*]One should grasp the meaning of the matter, only then can it be considered that the reading is complete. [/list]

[b]2. Just Say No!-[/b] Gout is caused by poor lifestyle choices. Unfortunately, gout prevention occurs by just saying no! Here is a quick list you should memorize. If you drink, only drink one drink per night. Particularly beer can lead to hyperuricemia because it interferes with the removal of uric acid. Also avoid processed foods, fast foods, and fried foods if at all possible.

[b]3. Alkaline Water-[/b] You should be drinking at least 10 to 12 eight-ounce glasses of non-alcoholic fluid every day. The fluid will help your body flush the crystals out of your system. Try drinking alkaline water with a pH of greater than 7. Thinking of life without Lower Uric Acid seem to be impossible to imagine. This is because Lower Uric Acid can be applied in all situations of life.

The reason why natural and holistic remedies are becoming popular is because science is now revealing that your body has an internal intelligence which allows itself to naturally heal if giving the proper tools. In the case of gout, it is curable with your diet, vitamins, supplements, some herbs and a few simple remedies.

[b]1. Decrease Uric Acid Levels-[/b] The first step for curing gout is to either flush the uric acid in your body or neutralize it. If you need immediate relief, you can eat certain fruits or even a baking soda drink to immediately lower the uric acid levels. If you are interested in curing gout permanently and losing 15+ lbs, you need to focus on your diet. I will discuss your diet in a second.

Therefore our gout remedy report would be considered 'holistic' because it is using your 'whole' body to flush the uric acid from your body and joints. By eliminating the high levels of uric acid, you can treat gout naturally. Just as a book shouldn't be judged by its cover, we wish you read this entire article on Uric Acid Levels before actually making a judgement about Uric Acid Levels.

[list][*][b]Cure Gout Naturally and Holistically[/b] Natural remedies have been around probably since the beginning of mankind.[*]And only in recent years has there been valid proof that many remedies have been shown to be quite effective (many were proven false too).[*]And did you know that gout is one of the easiest diseases to naturally treat?[*]We have tried to place the best definition about Gout in this article.[*]This has taken a lot of time, but we only wish that the definition we gave suits your needs.[/list]
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